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Author | ROTHWELL |
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Table Of Content | Section 1: Reliable determination of the overall effects of treatments 1) Reliable assessment of the effects of treatment on mortality and major morbidity 2) The lethal consequences of failing to make full use of all relevant evidence about the effects of medical treatments: the importance of systematic reviews Section 2: Is the trial relevant to this patient? 3) Assessment of the external validity of randomised trials 4) Applying results to treatment decisions in primary care 5) The older patient 6) Applying results to treatment decisions in complex clinical situations 7) External validity of pharmaceutical trials in neuropathic pain 8) External validity of pharmaceutical trials in asthma and chronic obstructive pulmonary disease Section 3: Is the overall trial result sufficiently relevant this patient? 9) When should we expect clinically important differences in response to treatment? 10) Genes and the individual response to treatment 11) Reliable estimation and interpretation of the effects of treatment in subgroups 12) Can meta-analysis help target interventions at individuals most likely to benefit? 13) Use of risk models to predict the likely effects of treatment in individuals 14) Evaluating the performance of prognostic models 15) Are "n-of-1" trials of any practical value to clinicians or researchers? Section 4: Targeting of treatment in routine practice 16) Primary prevention of cardiovascular disease: the absolute risk-based approach 17) Antithrombotic therapy to prevent stroke in patients with atrial fibrillation 18) Reperfusion therapies in acute cardiovascular and cerebrovascular syndromes 19) Choice of agent in treatment of epilepsy 20) Pharmacogenomic targeting of treatment for cancer |
Format | 234 x 156 (6 1/8 x 9 1/4) |
Page Count | 340 |
Publish Date | 2 Jul 2007 |