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Health for all Children

Health for all Children

Advancing the Science of Implementation across the Cancer Cancer Continuum

Advancing the Science of Implementation across the Cancer Cancer Continuum

Psychiatric Epidemiology Searching for the Causes of Mental Disorders

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9780195101812
 

Searching for the causes of mental disorders is as exciting as it is complex. The relationship between pathophysiology and its overt manifestations is exceedingly intricate, and often the causes of a disorder are elusive at best. This book is an invaluable resource for anyone trying to track these causes, whether they be clinical researchers, public health practitioners, or psychiatric epidemiologists-in-training. Uniting theory and practice in very clear language, it makes a wonderful contribution to both epidemiologic and psychiatric research. Rather than attempting to review the descriptive epidemiology of mental disorders, this book gives a much more dynamic exposition of the thinking and techniques used to establish it.

Starting out by tracing the brief history of psychiatric epidemiology, the book describes the study of risk factors as causes of mental disorders. Subsequent sections discuss approaches to investigation of biologic, genetic or social causes and the statistical analysis of study results. The book concludes by following some of the problems involved in the search for genetic causes of mental disorders, and more complex causal relationships.

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Author SUSSER
Table Of Content

Part I Psychiatric Epidemiology, Then and Now
1: The Burden of Mental Illness
2: The Arc of Epidemiology
3: Searching for the Causes of Mental Disorders
Part II Risk Factors as Causes of Mental Disorders
4: What Is a Cause?
5: Detecting Causes
6: Study Designs
7: Relationships among Causes
8: Measures of Association
Part III Cohort Designs in Psychiatric Epidemiology
9: Prototypical Cohort Study
10: Diversity of Cohort Studies
11: Causal Interference: A Thought Experiment
12: Confounding: What It Is and What Can Be Done
13: Unequal Attrition under Different Types of Follow-Up
14: Differential Misclassification
Part IV Case-Control Designs in Psychiatric Epidemiology
15: Logic of the Case-Control Design
16: Applications of the Case-Control Study
17: Choosing Controls
18: Comparability and the Case-Control Study
Part V Case-Control Designs in Biologic Psychiatry, Contributions to Part V by Jack M. Gorman
19: Biologic Studies in Psychiatry
20: Choosing Cases in Biologic Psychiatry
21: Choosing Controls in Biologic Psychiatry
Part VI Analyzing the Data, Contributions to Part VI by Melissa D. Begy
22: Gauging the Precision of Measures of Association
23: Using Significance Tests in Establishing Associations
24: Planning Studies: Estimating Power and Sample Size
25: Adjustment for Covariates
26: Event Time Analysis
27: Assessing Heterogeneity of Effects
Part VII The Search for Genetic Causes of Mental Disorders, Contributions to Part VII by Mary-Claire King
28: Integrating Epidemiology with Genetics
29: Genetic Association Studies
30: Modern Family History Studies
31: Twin Studies of Heritability
32: Genetic Linkage Studies
33: Designs for the Genomic Era
Part VIII Complex Causal Relationships
34: Eco-Epidemiology
35: Causal Explanation within a Risk Factor Framework
36: Causal Explanation Outside the Black Box
37: Dependent and Dynamic Processes
Appendix A. Our Approach to Epidemiologic Concepts and Methods
Appendix B. Application of Survival Analysis to Prenatal Determinants of Schizophrenia Example (PDSE) Data

Publish Date 29 Jun 2006
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