Free shipping on orders over $500 throughout NSW and to all interstate Capitals.
Currency
Toggle Nav
Homocysteine in Health and Disease
Regular Price
$132.95
Special Price
$119.65
$108.77
This is an unusually comprehensive 2001 account of the broad range of medical implications of homocysteine.
Stock Status:
Out of stock
Availability:
Out of stock
SKU
9781107402423
High levels of homocysteine, a sulfur-containing amino acid derived from methionine, have recently been identified as a very important risk factor in cardiovascular disease. Homocysteine abnormalities are also thought to contribute to birth defects and dementia. There are many common genetic disorders and problems (such as vitamin deficiency) that adversely affect the metabolism of homocysteine. In this book a team of the world's experts in the field provide a clear, current, clinical analysis of the biochemistry, genetics, and epidemiology of homocysteine disorders, providing a uniquely comprehensive account of the broad range of medical, nutritional and methodological implications of homocysteine for health and disease.
| Author | Edited by Ralph Carmel , Donald W. Jacobsen |
|---|---|
| Table Of Content | 1. Introduction: historical overview and recent perspectives David Wilken and Bridget Wilken Part I. Biochemistry and Physiology Section I. Chemistry: 2. Practical chemistry of homocysteine and other thiols Donald W. Jacobsen 3. Biosynthesis and reactions of homocysteine thiolactone Hieronim Jakubowski 4. Homocysteine and lipid oxidation Jay W. Heinecke 5. Homocysteine, nitric oxide and nitrosothiols Andrew J. Gow, Fred Cobb and Jonathan S. Stamler Section II. Biochemistry and metabolism: 6. Biosynthesis of S-adenosylmethionine Jose M. Mato, Matias A. Avila and Fernado J. Corrales 7. S-adenosylmethionine-dependent methyltransferase Steven G. Clarke and Kelly Banfield 8. S-adenosylhomosysteine hydrolase Sean T. Prigge and Peter K. Chiang 9. Regulation of homocysteine metabolism James D. Finkelstein 10. Microbial modeling of human disease: homocysteine metabolism Rowena G. Matthews and Martha L. Ludwig 11. Folate metabolism Robert J. Cook 12. Cobalamin-dependent remethylation Ruma V. Banerjee and Horatiu Olteanu 13. Betaine-dependent remethylation Tim Garrow 14. The transsulfuration pathway Warren D. Kruger Section III. Physiology: 15. Cellular transport and tissue distribution Brian Fowler 16. Homocysteine and the kidney John T. Brosnan 17. Homocysteine and the nervous system Anne M. Molloy and Donald G. Weir Section IV. Clinical Chemistry: 18. Methodologies of testing Karsten Rasmussen and Jan Möller 19. Methionine loading Nicholas Dudman and Jonathan Silberberg Part II. Clinical Dysfunction and Hyperhomocysteinemia Section V. Genetic Disorders: 20. Cystathionine-ß-synthase and its deficiency Jan P. Kraus and Viktor Kozich 21. Inborn errors of folate and cobalamin metabolism David S. Rosenblatt 22. Polymorphisms of folate and cobalamin metabolism Rima Rozen Section VI. Acquired Disorders: 23. Folate deficiency Ralph Carmel 24. Cobalamin deficiency Ralph Carmel 25. Vitamin B6 deficiency Jesse F. Gregory III 26. Homocysteine in renal disease Margret Arnadottir and Björn Hultberg 27. Diseases and drugs associated with hyperhomocysteinemia Henk J. Blom 28. Lifestyle factors associated with hyperhomocysteinemia Stein Emil Vollset, Helga Refsum, Ottar Nygard and Per Ueland Section VII. Clinical Consequences of Hyperhomocysteinemia: 29. Epidemiology: vascular and thrombotic associations Petra Verhoef and Meir Stampfer 30. Homocysteine and coronary artery disease Killian Robinson 31. Homocysteine and cerebrovascular disease J. David Spence and James F. Toole 32. Peripheral arterial disease Godfried Boers 33. Venous disease Armando D'Angelo and Chiara Beltrametti 34. Homocysteine and hemostasis Katherine A. Hajjar 35. Cellular mechanisms of homocysteine pathogenesis in atherosclerosis Donald W. Jacobsen 36. Homocysteine and cardiovascular physiology Steven R. Lentz 37. Homocysteine and human reproduction T. K. A. B. Eskes Section VIII. Intervention and Therapy: 38. Modification of hyperhomocysteinemia John M. Scott 39. Design of clinical trials to test the homocysteine hypothesis of vascular disease Robert Clarke 40. What is a desirable homocysteine level? Johan B. Ubbink Index. |
| Format | Paperback |
| Publish Date | 21 Jul 2011 |
Write Your Own Review