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Genomic Imprinting
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$67.95
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$61.15
$55.59
This significant 1995 publication deals with genomic or parental imprinting.
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Out of stock
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9780521179997
Genomic imprinting results in the preferential expression of one gene, depending on the parent of origin, and it is associated with several disease syndromes in humans. This book covers a wealth of research material on chromatin structure, epigenetics, clinical genetics, developmental biology, cancer, hypotheses of evolution, and the molecular basis of the imprinting process, which will help explain not only the mechanisms of genomic imprinting, but also its biological and medical consequences.
| Author | Edited by R. Ohlsson , K. Hall , M. Ritzen |
|---|---|
| Table Of Content | Contributors Part I. Genomic Imprinting in Mammals: 1. The role of imprinting in early mammalian development A. Gilligan, and D. Solter 2. The evolution of parental imprinting: a review of hypotheses D. Haig and R. Trivers 3. Genetic variations in parental imprinting on mouse chromosome 17 J. Forejt, S. Gregorovà, M. Landíková, J. Capková and L. M. Silver Part II. Chromatin Structure and DNA Modifications: 4. Epigenetic inheritance: the chromatin connection A. P. Wolffe 5. Chromobox genes and the molecular mechanisms of cellular determination P. B. Singh and T. C. James 6. The biochemical basis of allele-specific gene expression in genomic imprinting and X inactivation T. H. Bestor 7. DNA methylation and mammalian development R. Jaenisch, C. Beard and E. Li Part III. Mechanisms of Imprinting: 8. X chromosome inactivation and imprinting M. F. Lyon 9. Imprinting of H19 and Xist in uniparental embryos M. A. Surani, A. C. Ferguson-Smith, H. Sasaki and S. C. Barton 10. Imprinted genes, allelic methylation, and imprinted modifiers of methylation W. Reik, R. Feil, N. D. Allen, T. F. Moore and J. Walter 11. Genomic imprinting of the H19 and Igf2 genes in the mouse S. M. Tilgham, M. S. Bartolomei, A. L. Webber, M. E. Brunkow, J. Saam, P. A. Leighton and K. Pfeifer 12. Plasticity of imprinting R. Ohlsson, T. Ekström, G. Franklin, S. Pfeifer-Ohlsson, H. Cui, S. Miller, R. Fisher and C. Walsh 13. Regional regulation of allele-specific gene expression I. Simon and H. Cedar Part IV. Genomic Imprinting in Embryonal Tumors and Overgrowth Disorders: 14. Genomic imprinting in embryonal tumors and overgrowth disorders A. E. Reeve 15. Tracking imprinting: the Beckwith-Wiedemann syndrome M. Mannens 16. Genomic imprinting in Beckwith-Wiedemann syndrome R. Weksberg and J. Squire 17. Mitotic crossing over and the disruption of genomic imprinting G. B. Côté 18. Evaluating H19 as an imprinted tumor suppressor gene B. Tycko 19. A domain of abnormal imprinting in human cancer A. P. Feinberg Part V. Genomic Imprinting and the Prader-Willi Syndrome: 20. Parent-of-origin-specific DNA methylation and imprinting mutations on human chromosome 15 B. Horsthemke, B. Dittrich and K. Buiting 21. The SNRPN gene and Prader-Willi syndrome U. Francke, J. A. Kerns and J. Giacalone Part VI. Imprinting: A Search for New Genes and Unifying Principles: 22. Use of chromosome rearrangements for investigations into imprinting in the mouse B. M. Cattanach, J. Barr and J. Jones 23. A new imprinted gene, U2af-related sequence, isolated by a methylation-sensitive genome scanning method T. Mukai, I. Hatada, T. Yamaoka, K. Kitagawa, X.-D. Wang, T. Sugama, J. Masuda and J. Ogata 24. The mouse Igf2/MPR gene: a model for all gametic imprinted genes? D. P. Barlow Index. |
| Format | Paperback |
| Publish Date | 17 Feb 2011 |
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